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Kinetics of FcRn-mediated recycling of IgG and albumin in human: pathophysiology and therapeutic implications using a simplified mechanism-based model

Receptor activation triggers an adenylyl-cyclase / cAMP / protein-kinase-A signalling cascade, leading to vesicular release of growth hormone from somatotroph storage pools

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Because of this variability, outcomes may range from comparable to subtherapeutic or uncomfortable

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